Production of biologically active IL‐36 family cytokines through insertion of N‐terminal caspase cleavage motifs
نویسندگان
چکیده
منابع مشابه
Production of biologically active IL‐36 family cytokines through insertion of N‐terminal caspase cleavage motifs
Recent evidence has strongly implicated IL-36 cytokines as key initiators of inflammation in the skin barrier. IL-36 cytokines belong to the extended IL-1 family and, similar to most members of this family, are expressed as inactive precursors that require proteolytic processing for activation. Because the proteases responsible for activation of members of the IL-36 subfamily have not been repo...
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ژورنال
عنوان ژورنال: FEBS Open Bio
سال: 2016
ISSN: 2211-5463,2211-5463
DOI: 10.1002/2211-5463.12044